Neuronal cell lines expressing PC5, but not PC1 or PC2, process Pro-CCK into glycine-extended CCK 12 and 22. [electronic resource]
Producer: 20011025Description: 1271-7 p. digitalISSN:- 0196-9781
- Animals
- Aspartic Acid Endopeptidases -- biosynthesis
- Blotting, Western
- Brain -- metabolism
- Cell Line
- Cholecystokinin -- metabolism
- Chromatography, Gel
- Genetic Vectors
- Glycine -- chemistry
- Humans
- Intestinal Mucosa -- metabolism
- Mice
- Neurons -- metabolism
- Peptide Fragments -- metabolism
- Proprotein Convertase 1
- Proprotein Convertase 2
- Proprotein Convertase 5
- Proprotein Convertases
- Protein Precursors -- metabolism
- RNA, Messenger -- metabolism
- Radioimmunoassay
- Reverse Transcriptase Polymerase Chain Reaction
- Serine Endopeptidases -- biosynthesis
- Subtilisins -- biosynthesis
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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