Neuronal cell lines expressing PC5, but not PC1 or PC2, process Pro-CCK into glycine-extended CCK 12 and 22.

Cain, B M

Neuronal cell lines expressing PC5, but not PC1 or PC2, process Pro-CCK into glycine-extended CCK 12 and 22. [electronic resource] - Peptides Aug 2001 - 1271-7 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0196-9781

10.1016/s0196-9781(01)00451-x doi


Animals
Aspartic Acid Endopeptidases--biosynthesis
Blotting, Western
Brain--metabolism
Cell Line
Cholecystokinin--metabolism
Chromatography, Gel
Genetic Vectors
Glycine--chemistry
Humans
Intestinal Mucosa--metabolism
Mice
Neurons--metabolism
Peptide Fragments--metabolism
Proprotein Convertase 1
Proprotein Convertase 2
Proprotein Convertase 5
Proprotein Convertases
Protein Precursors--metabolism
RNA, Messenger--metabolism
Radioimmunoassay
Reverse Transcriptase Polymerase Chain Reaction
Serine Endopeptidases--biosynthesis
Subtilisins--biosynthesis
Tumor Cells, Cultured