IFN-gamma and Fas/FasL are required for the antitumor and antiangiogenic effects of IL-12/pulse IL-2 therapy. [electronic resource]
Producer: 20010809Description: 51-62 p. digitalISSN:- 0021-9738
- Angiogenesis Inhibitors -- administration & dosage
- Animals
- Antineoplastic Agents -- administration & dosage
- Apoptosis -- drug effects
- CD8-Positive T-Lymphocytes -- immunology
- Carcinoma, Renal Cell -- blood supply
- Combined Modality Therapy
- Drug Administration Schedule
- Endothelium, Vascular -- drug effects
- Fas Ligand Protein
- Immunologic Factors -- administration & dosage
- Injections, Intraperitoneal
- Interferon-gamma -- physiology
- Interleukin-12 -- administration & dosage
- Kidney Neoplasms -- blood supply
- Membrane Glycoproteins -- deficiency
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C3H
- Mice, Knockout
- Mice, Mutant Strains
- Neoplasm Metastasis
- Neoplasm Transplantation
- Neovascularization, Pathologic -- drug therapy
- Nephrectomy
- Recombinant Proteins -- administration & dosage
- Specific Pathogen-Free Organisms
- fas Receptor -- physiology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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