pRb suppresses camptothecin-induced apoptosis in human osteosarcoma Saos-2 cells by inhibiting c-Jun N-terminal kinase. [electronic resource]
Producer: 20010726Description: 191-7 p. digitalISSN:- 0014-5793
- Apoptosis -- drug effects
- Blotting, Western
- Camptothecin -- antagonists & inhibitors
- Caspase 3
- Caspases -- metabolism
- Cell Cycle -- drug effects
- Cell Size -- drug effects
- Cell Survival -- drug effects
- DNA Topoisomerases, Type I -- metabolism
- Dose-Response Relationship, Drug
- Enzyme Activation -- drug effects
- Flow Cytometry
- Glutathione -- metabolism
- Humans
- Hydrogen Peroxide -- metabolism
- JNK Mitogen-Activated Protein Kinases
- Mitogen-Activated Protein Kinases -- antagonists & inhibitors
- Oxidative Stress -- drug effects
- Phosphorylation -- drug effects
- Poly(ADP-ribose) Polymerases -- metabolism
- Proto-Oncogene Proteins c-jun -- metabolism
- Retinoblastoma Protein -- genetics
- Time Factors
- Topoisomerase I Inhibitors
- Transfection
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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