The anticonvulsant, antihyperalgesic agent gabapentin is an agonist at brain gamma-aminobutyric acid type B receptors negatively coupled to voltage-dependent calcium channels. [electronic resource]
Producer: 20010719Description: 15-24 p. digitalISSN:- 0022-3565
- Acetates -- pharmacology
- Amines
- Analgesics -- pharmacology
- Animals
- Anticonvulsants -- pharmacology
- Baclofen -- pharmacology
- Calcium Channels -- drug effects
- Calcium Signaling -- drug effects
- Cyclohexanecarboxylic Acids
- GABA Agonists -- pharmacology
- GABA-B Receptor Agonists
- Gabapentin
- Hippocampus -- drug effects
- Male
- Mice
- Mice, Transgenic
- Pyramidal Cells -- drug effects
- Rats
- Rats, Sprague-Dawley
- Receptors, GABA-B -- physiology
- gamma-Aminobutyric Acid
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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