The anticonvulsant, antihyperalgesic agent gabapentin is an agonist at brain gamma-aminobutyric acid type B receptors negatively coupled to voltage-dependent calcium channels.
Bertrand, S
The anticonvulsant, antihyperalgesic agent gabapentin is an agonist at brain gamma-aminobutyric acid type B receptors negatively coupled to voltage-dependent calcium channels. [electronic resource] - The Journal of pharmacology and experimental therapeutics Jul 2001 - 15-24 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
0022-3565
Acetates--pharmacology
Amines
Analgesics--pharmacology
Animals
Anticonvulsants--pharmacology
Baclofen--pharmacology
Calcium Channels--drug effects
Calcium Signaling--drug effects
Cyclohexanecarboxylic Acids
GABA Agonists--pharmacology
GABA-B Receptor Agonists
Gabapentin
Hippocampus--drug effects
Male
Mice
Mice, Transgenic
Pyramidal Cells--drug effects
Rats
Rats, Sprague-Dawley
Receptors, GABA-B--physiology
gamma-Aminobutyric Acid
The anticonvulsant, antihyperalgesic agent gabapentin is an agonist at brain gamma-aminobutyric acid type B receptors negatively coupled to voltage-dependent calcium channels. [electronic resource] - The Journal of pharmacology and experimental therapeutics Jul 2001 - 15-24 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
0022-3565
Acetates--pharmacology
Amines
Analgesics--pharmacology
Animals
Anticonvulsants--pharmacology
Baclofen--pharmacology
Calcium Channels--drug effects
Calcium Signaling--drug effects
Cyclohexanecarboxylic Acids
GABA Agonists--pharmacology
GABA-B Receptor Agonists
Gabapentin
Hippocampus--drug effects
Male
Mice
Mice, Transgenic
Pyramidal Cells--drug effects
Rats
Rats, Sprague-Dawley
Receptors, GABA-B--physiology
gamma-Aminobutyric Acid