The contribution of UDP-glucuronosyltransferase 1A9 on CYP1A2-mediated genotoxicity by aromatic and heterocyclic amines. [electronic resource]
Producer: 20010621Description: 943-50 p. digitalISSN:- 0143-3334
- 2-Acetylaminofluorene -- pharmacokinetics
- Animals
- Bacterial Proteins -- biosynthesis
- Biotransformation
- Catalysis
- Cell Line
- Cytochrome P-450 CYP1A2 -- genetics
- DNA-Directed DNA Polymerase
- Escherichia coli Proteins
- Gene Expression Regulation, Enzymologic -- drug effects
- Glucuronides -- biosynthesis
- Glucuronosyltransferase -- genetics
- Humans
- Hydroxyacetylaminofluorene -- pharmacokinetics
- Hydroxylation
- Imidazoles -- pharmacokinetics
- Isoenzymes -- genetics
- Mice
- Mutagenicity Tests
- Mutagens -- pharmacokinetics
- Pyridines -- pharmacokinetics
- Recombinant Proteins -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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