The contribution of UDP-glucuronosyltransferase 1A9 on CYP1A2-mediated genotoxicity by aromatic and heterocyclic amines.

Yueh, M F

The contribution of UDP-glucuronosyltransferase 1A9 on CYP1A2-mediated genotoxicity by aromatic and heterocyclic amines. [electronic resource] - Carcinogenesis Jun 2001 - 943-50 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0143-3334

10.1093/carcin/22.6.943 doi


2-Acetylaminofluorene--pharmacokinetics
Animals
Bacterial Proteins--biosynthesis
Biotransformation
Catalysis
Cell Line
Cytochrome P-450 CYP1A2--genetics
DNA-Directed DNA Polymerase
Escherichia coli Proteins
Gene Expression Regulation, Enzymologic--drug effects
Glucuronides--biosynthesis
Glucuronosyltransferase--genetics
Humans
Hydroxyacetylaminofluorene--pharmacokinetics
Hydroxylation
Imidazoles--pharmacokinetics
Isoenzymes--genetics
Mice
Mutagenicity Tests
Mutagens--pharmacokinetics
Pyridines--pharmacokinetics
Recombinant Proteins--genetics