KN-93 inhibition of G protein signaling is independent of the ability of Ca2+/calmodulin-dependent protein kinase II to phosphorylate phospholipase Cbeta3 on 537-Ser. [electronic resource]
Producer: 20011213Description: 149-56 p. digitalISSN:- 0303-7207
- Amino Acid Substitution
- Animals
- Benzylamines -- pharmacology
- Binding Sites
- Calcium-Calmodulin-Dependent Protein Kinase Type 2
- Calcium-Calmodulin-Dependent Protein Kinases -- pharmacology
- Enzyme Inhibitors -- pharmacology
- Heterotrimeric GTP-Binding Proteins -- antagonists & inhibitors
- Isoenzymes -- drug effects
- Phosphatidylinositols -- metabolism
- Phospholipase C beta
- Phosphorylation
- Rats
- Serine -- metabolism
- Signal Transduction -- drug effects
- Sulfonamides -- pharmacology
- Transfection
- Tumor Cells, Cultured
- Type C Phospholipases -- drug effects
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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