Replicative senescence of biliary epithelial cells precedes bile duct loss in chronic liver allograft rejection: increased expression of p21(WAF1/Cip1) as a disease marker and the influence of immunosuppressive drugs. [electronic resource]
Producer: 20010503Description: 1379-90 p. digitalISSN:- 0002-9440
- Animals
- Antibodies -- pharmacology
- Bile Ducts -- pathology
- Biomarkers
- Cell Division -- drug effects
- Cellular Senescence -- physiology
- Chronic Disease
- Cyclin-Dependent Kinase Inhibitor p21
- Cyclins -- metabolism
- Cyclosporine -- pharmacology
- Epithelial Cells -- pathology
- Graft Rejection -- drug therapy
- Humans
- Immunosuppressive Agents -- therapeutic use
- Intracellular Membranes -- metabolism
- Liver Transplantation
- Male
- Mice
- RNA, Messenger -- metabolism
- Signal Transduction -- physiology
- Tacrolimus -- pharmacology
- Time Factors
- Transforming Growth Factor beta -- genetics
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Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.
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