Carbachol restores insulin release in diabetic GK rat islets by mechanisms largely involving hydrolysis of diacylglycerol and direct interaction with the exocytotic machinery. [electronic resource]
Producer: 20010607Description: 164-71 p. digitalISSN:- 0885-3177
- Animals
- Arachidonic Acid -- biosynthesis
- Carbachol -- pharmacology
- Cholinergic Agonists -- pharmacology
- Cyclic AMP -- biosynthesis
- Diabetes Mellitus -- metabolism
- Diglycerides -- metabolism
- Exocytosis
- Hydrolysis
- Insulin -- metabolism
- Insulin Secretion
- Islets of Langerhans -- drug effects
- Male
- Perfusion
- Protein Kinase C -- physiology
- Rats
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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