Carbachol restores insulin release in diabetic GK rat islets by mechanisms largely involving hydrolysis of diacylglycerol and direct interaction with the exocytotic machinery.

Guenifi, A

Carbachol restores insulin release in diabetic GK rat islets by mechanisms largely involving hydrolysis of diacylglycerol and direct interaction with the exocytotic machinery. [electronic resource] - Pancreas Mar 2001 - 164-71 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0885-3177

10.1097/00006676-200103000-00009 doi


Animals
Arachidonic Acid--biosynthesis
Carbachol--pharmacology
Cholinergic Agonists--pharmacology
Cyclic AMP--biosynthesis
Diabetes Mellitus--metabolism
Diglycerides--metabolism
Exocytosis
Hydrolysis
Insulin--metabolism
Insulin Secretion
Islets of Langerhans--drug effects
Male
Perfusion
Protein Kinase C--physiology
Rats