Cutting edge: targeted disruption of the C3a receptor gene demonstrates a novel protective anti-inflammatory role for C3a in endotoxin-shock. [electronic resource]
Producer: 20001222Description: 5406-9 p. digitalISSN:- 0022-1767
- Amino Acid Sequence
- Animals
- Anti-Inflammatory Agents, Non-Steroidal -- immunology
- Complement C3a -- metabolism
- Dose-Response Relationship, Immunologic
- Gene Targeting -- methods
- Genetic Predisposition to Disease
- Injections, Intravenous
- Interleukin-1 -- biosynthesis
- Lipopolysaccharides -- toxicity
- Membrane Proteins
- Mice
- Mice, Inbred C57BL
- Mice, Inbred Strains
- Mice, Knockout
- Molecular Sequence Data
- Mutagenesis, Insertional
- Receptors, Complement -- deficiency
- Shock, Septic -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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