Cutting edge: targeted disruption of the C3a receptor gene demonstrates a novel protective anti-inflammatory role for C3a in endotoxin-shock.

Kildsgaard, J

Cutting edge: targeted disruption of the C3a receptor gene demonstrates a novel protective anti-inflammatory role for C3a in endotoxin-shock. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) Nov 2000 - 5406-9 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0022-1767

10.4049/jimmunol.165.10.5406 doi


Amino Acid Sequence
Animals
Anti-Inflammatory Agents, Non-Steroidal--immunology
Complement C3a--metabolism
Dose-Response Relationship, Immunologic
Gene Targeting--methods
Genetic Predisposition to Disease
Injections, Intravenous
Interleukin-1--biosynthesis
Lipopolysaccharides--toxicity
Membrane Proteins
Mice
Mice, Inbred C57BL
Mice, Inbred Strains
Mice, Knockout
Molecular Sequence Data
Mutagenesis, Insertional
Receptors, Complement--deficiency
Shock, Septic--genetics