The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism. [electronic resource]
Producer: 20001109Description: 920-3 p. digitalISSN:- 0028-0836
- Alanine Transaminase -- biosynthesis
- Animals
- Aryl Hydrocarbon Hydroxylases
- Cell Line
- Cocaine -- toxicity
- Coxsackie and Adenovirus Receptor-Like Membrane Protein
- Cytochrome P-450 Enzyme System -- biosynthesis
- Cytochrome P450 Family 2
- Enzyme Induction
- Female
- Gene Expression Regulation, Enzymologic -- drug effects
- Gene Targeting
- Humans
- Liver -- drug effects
- Male
- Mice
- Pharmaceutical Preparations -- metabolism
- Phenobarbital -- chemistry
- Pyridines -- pharmacology
- Receptors, Virus -- deficiency
- Steroid Hydroxylases
- Xenobiotics -- chemistry
- Zoxazolamine -- metabolism
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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