SB 239063, a p38 MAPK inhibitor, reduces neutrophilia, inflammatory cytokines, MMP-9, and fibrosis in lung. [electronic resource]
Producer: 20001109Description: L895-902 p. digitalISSN:- 1040-0605
- Animals
- Bleomycin -- toxicity
- Cells, Cultured
- Cytokines -- biosynthesis
- Disease Models, Animal
- Enzyme Inhibitors -- pharmacology
- Guinea Pigs
- Humans
- Hypertension, Pulmonary -- chemically induced
- Imidazoles -- pharmacology
- Inflammation -- physiopathology
- Interleukin 1 Receptor Antagonist Protein
- Interleukin-1 -- blood
- Interleukin-6 -- blood
- Interleukin-8 -- blood
- Lipopolysaccharides -- toxicity
- Lung -- drug effects
- Lung Diseases, Obstructive -- physiopathology
- Male
- Matrix Metalloproteinase 9 -- metabolism
- Mitogen-Activated Protein Kinases -- antagonists & inhibitors
- Neutrophils -- drug effects
- Pulmonary Alveoli -- drug effects
- Pulmonary Fibrosis -- chemically induced
- Pyrimidines -- pharmacology
- Rats
- Rats, Inbred Lew
- Sialoglycoproteins -- blood
- Tumor Necrosis Factor-alpha -- metabolism
- p38 Mitogen-Activated Protein Kinases
No physical items for this record
Publication Type: Journal Article
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