Effects of metal ions on the activity of protein tyrosine phosphatase VHR: highly potent and reversible oxidative inactivation by Cu2+ ion. [electronic resource]
Producer: 20001113Description: 72-80 p. digitalISSN:- 0003-9861
- Binding Sites
- Copper -- metabolism
- Cysteine -- chemistry
- Dithiothreitol -- pharmacology
- Dose-Response Relationship, Drug
- Dual Specificity Phosphatase 3
- Electrophoresis, Polyacrylamide Gel
- Enzyme Activation
- Glutathione -- metabolism
- Hydrogen Peroxide -- pharmacology
- Ions
- Mass Spectrometry
- Models, Chemical
- Mutagenesis, Site-Directed
- Oxygen -- metabolism
- Protein Tyrosine Phosphatases -- antagonists & inhibitors
- Time Factors
- Zinc -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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