Effects of metal ions on the activity of protein tyrosine phosphatase VHR: highly potent and reversible oxidative inactivation by Cu2+ ion.

Kim, J H

Effects of metal ions on the activity of protein tyrosine phosphatase VHR: highly potent and reversible oxidative inactivation by Cu2+ ion. [electronic resource] - Archives of biochemistry and biophysics Oct 2000 - 72-80 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0003-9861

10.1006/abbi.2000.1996 doi


Binding Sites
Copper--metabolism
Cysteine--chemistry
Dithiothreitol--pharmacology
Dose-Response Relationship, Drug
Dual Specificity Phosphatase 3
Electrophoresis, Polyacrylamide Gel
Enzyme Activation
Glutathione--metabolism
Hydrogen Peroxide--pharmacology
Ions
Mass Spectrometry
Models, Chemical
Mutagenesis, Site-Directed
Oxygen--metabolism
Protein Tyrosine Phosphatases--antagonists & inhibitors
Time Factors
Zinc--metabolism