Expression of the alpha 5 integrin subunit gene promoter is positively regulated by the extracellular matrix component fibronectin through the transcription factor Sp1 in corneal epithelial cells in vitro. [electronic resource]
Producer: 20010208Description: 39182-92 p. digitalISSN:- 0021-9258
- Animals
- Antigens, CD -- genetics
- Base Sequence
- Blotting, Western
- Cell Line
- Cell Nucleus -- metabolism
- Cells, Cultured
- Chloramphenicol O-Acetyltransferase -- metabolism
- Cornea -- metabolism
- DNA -- metabolism
- Dose-Response Relationship, Drug
- Drosophila
- Electrophoresis, Polyacrylamide Gel
- Enzyme Inhibitors -- pharmacology
- Epithelial Cells -- metabolism
- Extracellular Matrix -- metabolism
- Fibronectins -- metabolism
- Flavonoids -- pharmacology
- Gene Expression Regulation
- HeLa Cells
- Humans
- Integrin alpha5
- Ligands
- MAP Kinase Kinase Kinase 1
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Phosphorylation
- Plasmids -- metabolism
- Promoter Regions, Genetic
- Protein Binding
- Protein Serine-Threonine Kinases -- antagonists & inhibitors
- Rabbits
- Sequence Homology, Nucleic Acid
- Signal Transduction
- Sp1 Transcription Factor -- metabolism
- Transfection
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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