A novel function for the tumor suppressor p16(INK4a): induction of anoikis via upregulation of the alpha(5)beta(1) fibronectin receptor. [electronic resource]
Producer: 20001012Description: 1467-78 p. digitalISSN:- 0021-9525
- Animals
- Apoptosis -- drug effects
- Carrier Proteins -- genetics
- Cell Adhesion -- drug effects
- Cell Division -- physiology
- Cyclin-Dependent Kinase 4
- Cyclin-Dependent Kinase Inhibitor p16
- Cyclin-Dependent Kinases -- metabolism
- Down-Regulation -- physiology
- Fibronectins -- pharmacology
- Flow Cytometry
- Gene Expression Regulation, Neoplastic
- Genes, Tumor Suppressor -- physiology
- Humans
- In Vitro Techniques
- Kidney -- cytology
- Liver -- cytology
- Mice
- Mice, Nude
- Neoplasm Transplantation
- Pancreatic Neoplasms
- Phenotype
- Proto-Oncogene Proteins
- Receptors, Fibronectin -- metabolism
- Skin -- cytology
- Transfection
- Tumor Cells, Cultured
- Up-Regulation -- physiology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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