A novel function for the tumor suppressor p16(INK4a): induction of anoikis via upregulation of the alpha(5)beta(1) fibronectin receptor.
Plath, T
A novel function for the tumor suppressor p16(INK4a): induction of anoikis via upregulation of the alpha(5)beta(1) fibronectin receptor. [electronic resource] - The Journal of cell biology Sep 2000 - 1467-78 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0021-9525
10.1083/jcb.150.6.1467 doi
Animals
Apoptosis--drug effects
Carrier Proteins--genetics
Cell Adhesion--drug effects
Cell Division--physiology
Cyclin-Dependent Kinase 4
Cyclin-Dependent Kinase Inhibitor p16
Cyclin-Dependent Kinases--metabolism
Down-Regulation--physiology
Fibronectins--pharmacology
Flow Cytometry
Gene Expression Regulation, Neoplastic
Genes, Tumor Suppressor--physiology
Humans
In Vitro Techniques
Kidney--cytology
Liver--cytology
Mice
Mice, Nude
Neoplasm Transplantation
Pancreatic Neoplasms
Phenotype
Proto-Oncogene Proteins
Receptors, Fibronectin--metabolism
Skin--cytology
Transfection
Tumor Cells, Cultured
Up-Regulation--physiology
A novel function for the tumor suppressor p16(INK4a): induction of anoikis via upregulation of the alpha(5)beta(1) fibronectin receptor. [electronic resource] - The Journal of cell biology Sep 2000 - 1467-78 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0021-9525
10.1083/jcb.150.6.1467 doi
Animals
Apoptosis--drug effects
Carrier Proteins--genetics
Cell Adhesion--drug effects
Cell Division--physiology
Cyclin-Dependent Kinase 4
Cyclin-Dependent Kinase Inhibitor p16
Cyclin-Dependent Kinases--metabolism
Down-Regulation--physiology
Fibronectins--pharmacology
Flow Cytometry
Gene Expression Regulation, Neoplastic
Genes, Tumor Suppressor--physiology
Humans
In Vitro Techniques
Kidney--cytology
Liver--cytology
Mice
Mice, Nude
Neoplasm Transplantation
Pancreatic Neoplasms
Phenotype
Proto-Oncogene Proteins
Receptors, Fibronectin--metabolism
Skin--cytology
Transfection
Tumor Cells, Cultured
Up-Regulation--physiology