The HIV-1 coat protein gp120 and some of its fragments potently activate native cerebral NMDA receptors mediating neuropeptide release. [electronic resource]
Producer: 20001019Description: 2839-46 p. digitalISSN:- 0953-816X
- 2-Amino-5-phosphonovalerate -- pharmacology
- Animals
- Cerebral Cortex -- cytology
- Cholecystokinin -- metabolism
- Dizocilpine Maleate -- pharmacology
- Enzyme Inhibitors -- pharmacology
- Excitatory Amino Acid Antagonists -- pharmacology
- HIV Envelope Protein gp120 -- chemistry
- HIV-1
- Indoles -- pharmacology
- Kynurenic Acid -- analogs & derivatives
- Male
- Maleimides -- pharmacology
- Neurons -- metabolism
- Nitroarginine -- pharmacology
- Peptide Fragments -- metabolism
- Pipecolic Acids -- pharmacology
- Piperazines -- pharmacology
- Piperidines -- pharmacology
- Potassium -- pharmacology
- Protein Structure, Tertiary
- Rats
- Rats, Sprague-Dawley
- Receptors, N-Methyl-D-Aspartate -- metabolism
- Somatostatin -- metabolism
- Synaptic Transmission -- drug effects
- Synaptosomes -- metabolism
- Zinc -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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