Simvastatin modulates cytokine-mediated endothelial cell adhesion molecule induction: involvement of an inhibitory G protein. [electronic resource]
Producer: 20000919Description: 2712-8 p. digitalISSN:- 0022-1767
- Adjuvants, Immunologic -- pharmacology
- Biological Transport -- drug effects
- Cell Adhesion Molecules -- biosynthesis
- Cells, Cultured
- Cholesterol -- biosynthesis
- Cytokines -- physiology
- Drug Synergism
- E-Selectin -- biosynthesis
- Endothelium, Vascular -- drug effects
- GTP-Binding Protein alpha Subunits, Gi-Go -- physiology
- Gene Expression Regulation -- drug effects
- Humans
- Hydroxymethylglutaryl-CoA Reductase Inhibitors -- pharmacology
- Intercellular Adhesion Molecule-1 -- biosynthesis
- Interleukin-1 -- antagonists & inhibitors
- NF-kappa B -- metabolism
- RNA, Messenger -- metabolism
- Signal Transduction -- immunology
- Simvastatin -- pharmacology
- Sodium Fluoride -- pharmacology
- Umbilical Veins
- Vascular Cell Adhesion Molecule-1 -- biosynthesis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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