Simultaneous determination of urinary free cortisol and 6beta-hydroxycortisol by liquid chromatography-atmospheric pressure chemical ionization tandem mass spectrometry and its application for estimating hepatic CYP3A induction. [electronic resource]
Producer: 20001101Description: 303-13 p. digitalISSN:- 1387-2273
- Animals
- Aryl Hydrocarbon Hydroxylases
- Atmospheric Pressure
- Chromatography, High Pressure Liquid -- methods
- Corticosterone -- analogs & derivatives
- Cytochrome P-450 CYP3A
- Cytochrome P-450 Enzyme System -- biosynthesis
- Enzyme Induction
- Hydrocortisone -- urine
- Liver -- enzymology
- Macaca mulatta
- Mass Spectrometry -- methods
- Models, Animal
- Oxidoreductases, N-Demethylating -- biosynthesis
- Phenobarbital -- pharmacology
- Rifampin -- pharmacology
- Sensitivity and Specificity
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Publication Type: Journal Article; Validation Study
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