Simultaneous determination of urinary free cortisol and 6beta-hydroxycortisol by liquid chromatography-atmospheric pressure chemical ionization tandem mass spectrometry and its application for estimating hepatic CYP3A induction.
Tang, C
Simultaneous determination of urinary free cortisol and 6beta-hydroxycortisol by liquid chromatography-atmospheric pressure chemical ionization tandem mass spectrometry and its application for estimating hepatic CYP3A induction. [electronic resource] - Journal of chromatography. B, Biomedical sciences and applications Jun 2000 - 303-13 p. digital
Publication Type: Journal Article; Validation Study
1387-2273
10.1016/s0378-4347(00)00175-4 doi
Animals
Aryl Hydrocarbon Hydroxylases
Atmospheric Pressure
Chromatography, High Pressure Liquid--methods
Corticosterone--analogs & derivatives
Cytochrome P-450 CYP3A
Cytochrome P-450 Enzyme System--biosynthesis
Enzyme Induction
Hydrocortisone--urine
Liver--enzymology
Macaca mulatta
Mass Spectrometry--methods
Models, Animal
Oxidoreductases, N-Demethylating--biosynthesis
Phenobarbital--pharmacology
Rifampin--pharmacology
Sensitivity and Specificity
Simultaneous determination of urinary free cortisol and 6beta-hydroxycortisol by liquid chromatography-atmospheric pressure chemical ionization tandem mass spectrometry and its application for estimating hepatic CYP3A induction. [electronic resource] - Journal of chromatography. B, Biomedical sciences and applications Jun 2000 - 303-13 p. digital
Publication Type: Journal Article; Validation Study
1387-2273
10.1016/s0378-4347(00)00175-4 doi
Animals
Aryl Hydrocarbon Hydroxylases
Atmospheric Pressure
Chromatography, High Pressure Liquid--methods
Corticosterone--analogs & derivatives
Cytochrome P-450 CYP3A
Cytochrome P-450 Enzyme System--biosynthesis
Enzyme Induction
Hydrocortisone--urine
Liver--enzymology
Macaca mulatta
Mass Spectrometry--methods
Models, Animal
Oxidoreductases, N-Demethylating--biosynthesis
Phenobarbital--pharmacology
Rifampin--pharmacology
Sensitivity and Specificity