Isoflurane increases the apparent agonist affinity of the nicotinic acetylcholine receptor by reducing the microscopic agonist dissociation constant. [electronic resource]
Producer: 20000328Description: 775-85 p. digitalISSN:- 0003-3022
- Algorithms
- Anesthetics, Inhalation -- pharmacology
- Animals
- Choline -- analogs & derivatives
- Cholinergic Agents -- metabolism
- Dansyl Compounds
- Fluorescent Dyes
- In Vitro Techniques
- Ion Channel Gating -- drug effects
- Isoflurane -- pharmacology
- Kinetics
- Membranes -- drug effects
- Nicotinic Agonists -- pharmacology
- Quaternary Ammonium Compounds
- Receptors, Nicotinic -- drug effects
- Spectrometry, Fluorescence
- Torpedo
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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