Calmodulin antagonists inhibit insulin-stimulated GLUT4 (glucose transporter 4) translocation by preventing the formation of phosphatidylinositol 3,4,5-trisphosphate in 3T3L1 adipocytes. [electronic resource]
Producer: 20000525Description: 317-26 p. digitalISSN:- 0888-8809
- 3T3 Cells -- drug effects
- Adipocytes -- drug effects
- Animals
- Calmodulin -- antagonists & inhibitors
- Glucose Transporter Type 1
- Glucose Transporter Type 4
- Insulin -- metabolism
- Insulin Receptor Substrate Proteins
- Mice
- Monosaccharide Transport Proteins -- drug effects
- Muscle Proteins
- Phosphatidylinositol 3-Kinases -- drug effects
- Phosphatidylinositol Phosphates -- metabolism
- Phosphoproteins -- metabolism
- Phosphorylation
- Precipitin Tests
- Protein Serine-Threonine Kinases
- Proto-Oncogene Proteins -- drug effects
- Proto-Oncogene Proteins c-akt
- Sulfonamides -- pharmacology
- Trifluoperazine -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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