Calmodulin antagonists inhibit insulin-stimulated GLUT4 (glucose transporter 4) translocation by preventing the formation of phosphatidylinositol 3,4,5-trisphosphate in 3T3L1 adipocytes.

Yang, C

Calmodulin antagonists inhibit insulin-stimulated GLUT4 (glucose transporter 4) translocation by preventing the formation of phosphatidylinositol 3,4,5-trisphosphate in 3T3L1 adipocytes. [electronic resource] - Molecular endocrinology (Baltimore, Md.) Feb 2000 - 317-26 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0888-8809

10.1210/mend.14.2.0425 doi


3T3 Cells--drug effects
Adipocytes--drug effects
Animals
Calmodulin--antagonists & inhibitors
Glucose Transporter Type 1
Glucose Transporter Type 4
Insulin--metabolism
Insulin Receptor Substrate Proteins
Mice
Monosaccharide Transport Proteins--drug effects
Muscle Proteins
Phosphatidylinositol 3-Kinases--drug effects
Phosphatidylinositol Phosphates--metabolism
Phosphoproteins--metabolism
Phosphorylation
Precipitin Tests
Protein Serine-Threonine Kinases
Proto-Oncogene Proteins--drug effects
Proto-Oncogene Proteins c-akt
Sulfonamides--pharmacology
Trifluoperazine--pharmacology