Development of a whole cell assay to measure methotrexate-induced inhibition of thymidylate synthase and de novo purine synthesis in leukaemia cells. [electronic resource]
Producer: 20000203Description: 321-8 p. digitalISSN:- 0006-2952
- Adenine -- biosynthesis
- Antimetabolites, Antineoplastic -- pharmacology
- Child
- Guanine -- biosynthesis
- Humans
- Inosine -- metabolism
- Leukemia -- metabolism
- Methotrexate -- pharmacology
- Precursor Cell Lymphoblastic Leukemia-Lymphoma -- metabolism
- Purines -- biosynthesis
- Thymidine -- metabolism
- Thymidylate Synthase -- antagonists & inhibitors
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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