Liddle's syndrome mutations disrupt cAMP-mediated translocation of the epithelial Na(+) channel to the cell surface. [electronic resource]
Producer: 20000128Description: 45-53 p. digitalISSN:- 0021-9738
- 1-Methyl-3-isobutylxanthine -- pharmacology
- Animals
- Biological Transport
- Cells, Cultured
- Cyclic AMP -- physiology
- Cystic Fibrosis Transmembrane Conductance Regulator -- physiology
- Epithelium -- metabolism
- Hypertension -- genetics
- Mesylates -- pharmacology
- Mutation
- Rats
- Rats, Inbred F344
- Sodium -- metabolism
- Sodium Channels -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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