Requirement for a kinase-specific chaperone pathway in the production of a Cdk9/cyclin T1 heterodimer responsible for P-TEFb-mediated tat stimulation of HIV-1 transcription. [electronic resource]
Producer: 20000131Description: 279-87 p. digitalISSN:- 0021-9258
- Benzoquinones
- Cell Cycle Proteins -- metabolism
- Chaperonins
- Cyclin T
- Cyclin-Dependent Kinase 9
- Cyclin-Dependent Kinases -- metabolism
- Cyclins -- metabolism
- DNA Polymerase II -- metabolism
- Dimerization
- Drosophila Proteins
- Enzyme Activation
- Gene Products, tat -- metabolism
- HIV-1 -- genetics
- HSP70 Heat-Shock Proteins -- metabolism
- HSP90 Heat-Shock Proteins -- metabolism
- Humans
- Lactams, Macrocyclic
- Molecular Chaperones -- metabolism
- Positive Transcriptional Elongation Factor B
- Protein Binding -- drug effects
- Protein Serine-Threonine Kinases -- metabolism
- Quinones -- pharmacology
- Species Specificity
- Transcription, Genetic
- tat Gene Products, Human Immunodeficiency Virus
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
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