Phosphoinositide 3-hydroxide kinase blockade enhances apoptosis in the Ewing's sarcoma family of tumors. [electronic resource]
Producer: 19991214Description: 5745-50 p. digitalISSN:- 0008-5472
- Androstadienes -- pharmacology
- Antineoplastic Agents -- antagonists & inhibitors
- Apoptosis -- genetics
- Caspase 3
- Caspases -- metabolism
- Cell Transformation, Neoplastic -- chemically induced
- DNA Fragmentation
- Doxorubicin -- antagonists & inhibitors
- Enzyme Activation -- drug effects
- Enzyme Inhibitors -- pharmacology
- Humans
- In Situ Nick-End Labeling
- Insulin-Like Growth Factor I -- pharmacology
- Neoplasm Proteins -- antagonists & inhibitors
- Phosphatidylinositol 3-Kinases -- metabolism
- Phosphoinositide-3 Kinase Inhibitors
- Protein Serine-Threonine Kinases -- physiology
- Proto-Oncogene Proteins
- Proto-Oncogene Proteins c-akt
- Receptor, IGF Type 1
- Sarcoma, Ewing -- enzymology
- Tumor Cells, Cultured -- drug effects
- Wortmannin
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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