Targeting topoisomerase I cleavage to specific sequences of DNA by triple helix-forming oligonucleotide conjugates. A comparison between a rebeccamycin derivative and camptothecin. [electronic resource]
Producer: 20000124Description: 785-90 p. digitalISSN:- 0764-4469
- Aminoglycosides
- Anti-Bacterial Agents -- chemistry
- Antineoplastic Agents -- chemistry
- Base Sequence
- Camptothecin -- chemistry
- DNA Topoisomerases, Type I -- metabolism
- Drug Design
- Enzyme Inhibitors -- pharmacology
- Humans
- Molecular Sequence Data
- Nucleic Acid Conformation
- Oligodeoxyribonucleotides -- chemistry
- Substrate Specificity
- Topoisomerase I Inhibitors
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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