Nepalolide A inhibits the expression of inducible nitric oxide synthase by modulating the degradation of IkappaB-alpha and IkappaB-beta in C6 glioma cells and rat primary astrocytes. [electronic resource]
Producer: 20000104Description: 345-56 p. digitalISSN:- 0007-1188
- Animals
- Anthracenes -- pharmacology
- Astrocytes -- drug effects
- Biotransformation -- drug effects
- Blotting, Western
- Brain Neoplasms -- metabolism
- Cell Survival -- drug effects
- Cells, Cultured
- DNA-Binding Proteins -- metabolism
- Depression, Chemical
- Electrophoresis
- Enzyme Inhibitors -- pharmacology
- Glioma -- metabolism
- I-kappa B Proteins
- Interferon-gamma -- antagonists & inhibitors
- NF-KappaB Inhibitor alpha
- NF-kappa B -- antagonists & inhibitors
- Nitric Oxide Synthase -- antagonists & inhibitors
- Nitric Oxide Synthase Type II
- Nitrites -- metabolism
- Oligonucleotides -- metabolism
- Precipitin Tests
- RNA, Messenger -- biosynthesis
- Rats
- Rats, Sprague-Dawley
- Recombinant Proteins
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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