Evidence for the involvement of the fatty acid and peroxisomal beta-oxidation pathways in the inhibition by dehydroepiandrosterone (DHEA) and induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and benz(a)anthracene (BA) of cytochrome P4501B1 (CYP1B1) in mouse embryo fibroblasts (C3H10T1/2 cells). [electronic resource]
Producer: 19991124Description: 89-100 p. digitalISSN:- 0300-8177
- 9,10-Dimethyl-1,2-benzanthracene -- metabolism
- Acyl-CoA Oxidase
- Animals
- Aryl Hydrocarbon Hydroxylases
- Benz(a)Anthracenes -- pharmacology
- Cytochrome P-450 CYP1B1
- Cytochrome P-450 Enzyme System -- biosynthesis
- Cytosol -- enzymology
- Dehydroepiandrosterone -- pharmacology
- Embryo, Mammalian -- cytology
- Enzyme Induction
- Fatty Acids -- metabolism
- Fibroblasts -- drug effects
- Gene Expression Regulation, Enzymologic -- drug effects
- Mice
- Oxidation-Reduction
- Oxidoreductases -- genetics
- Peroxisomes -- metabolism
- Polychlorinated Dibenzodioxins -- pharmacology
- Signal Transduction
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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