Evidence for the involvement of the fatty acid and peroxisomal beta-oxidation pathways in the inhibition by dehydroepiandrosterone (DHEA) and induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and benz(a)anthracene (BA) of cytochrome P4501B1 (CYP1B1) in mouse embryo fibroblasts (C3H10T1/2 cells).

Ikegwuonu, F I

Evidence for the involvement of the fatty acid and peroxisomal beta-oxidation pathways in the inhibition by dehydroepiandrosterone (DHEA) and induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and benz(a)anthracene (BA) of cytochrome P4501B1 (CYP1B1) in mouse embryo fibroblasts (C3H10T1/2 cells). [electronic resource] - Molecular and cellular biochemistry Aug 1999 - 89-100 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0300-8177

10.1023/a:1006954216233 doi


9,10-Dimethyl-1,2-benzanthracene--metabolism
Acyl-CoA Oxidase
Animals
Aryl Hydrocarbon Hydroxylases
Benz(a)Anthracenes--pharmacology
Cytochrome P-450 CYP1B1
Cytochrome P-450 Enzyme System--biosynthesis
Cytosol--enzymology
Dehydroepiandrosterone--pharmacology
Embryo, Mammalian--cytology
Enzyme Induction
Fatty Acids--metabolism
Fibroblasts--drug effects
Gene Expression Regulation, Enzymologic--drug effects
Mice
Oxidation-Reduction
Oxidoreductases--genetics
Peroxisomes--metabolism
Polychlorinated Dibenzodioxins--pharmacology
Signal Transduction