Intravenous allopurinol decreases myocardial oxygen consumption and increases mechanical efficiency in dogs with pacing-induced heart failure. [electronic resource]
Producer: 19990930Description: 437-45 p. digitalISSN:- 0009-7330
- Allopurinol -- administration & dosage
- Animals
- Cardiac Pacing, Artificial
- Cardiotonic Agents -- administration & dosage
- Consciousness
- Diastole -- drug effects
- Disease Progression
- Dogs
- Drug Evaluation, Preclinical
- Energy Metabolism
- Enzyme Inhibitors -- administration & dosage
- Heart Failure -- drug therapy
- Heart Rate -- drug effects
- Injections, Intravenous
- Male
- Muscle Proteins -- antagonists & inhibitors
- Myocardial Contraction -- drug effects
- Myocardium -- enzymology
- Oxidative Stress
- Oxygen Consumption -- drug effects
- Ventricular Function, Left -- drug effects
- Xanthine Oxidase -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
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