Intravenous allopurinol decreases myocardial oxygen consumption and increases mechanical efficiency in dogs with pacing-induced heart failure.
Ekelund, U E
Intravenous allopurinol decreases myocardial oxygen consumption and increases mechanical efficiency in dogs with pacing-induced heart failure. [electronic resource] - Circulation research Sep 1999 - 437-45 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0009-7330
10.1161/01.res.85.5.437 doi
Allopurinol--administration & dosage
Animals
Cardiac Pacing, Artificial
Cardiotonic Agents--administration & dosage
Consciousness
Diastole--drug effects
Disease Progression
Dogs
Drug Evaluation, Preclinical
Energy Metabolism
Enzyme Inhibitors--administration & dosage
Heart Failure--drug therapy
Heart Rate--drug effects
Injections, Intravenous
Male
Muscle Proteins--antagonists & inhibitors
Myocardial Contraction--drug effects
Myocardium--enzymology
Oxidative Stress
Oxygen Consumption--drug effects
Ventricular Function, Left--drug effects
Xanthine Oxidase--antagonists & inhibitors
Intravenous allopurinol decreases myocardial oxygen consumption and increases mechanical efficiency in dogs with pacing-induced heart failure. [electronic resource] - Circulation research Sep 1999 - 437-45 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0009-7330
10.1161/01.res.85.5.437 doi
Allopurinol--administration & dosage
Animals
Cardiac Pacing, Artificial
Cardiotonic Agents--administration & dosage
Consciousness
Diastole--drug effects
Disease Progression
Dogs
Drug Evaluation, Preclinical
Energy Metabolism
Enzyme Inhibitors--administration & dosage
Heart Failure--drug therapy
Heart Rate--drug effects
Injections, Intravenous
Male
Muscle Proteins--antagonists & inhibitors
Myocardial Contraction--drug effects
Myocardium--enzymology
Oxidative Stress
Oxygen Consumption--drug effects
Ventricular Function, Left--drug effects
Xanthine Oxidase--antagonists & inhibitors