The G464S amino acid substitution in Candida albicans sterol 14alpha-demethylase causes fluconazole resistance in the clinic through reduced affinity. [electronic resource]
Producer: 19990923Description: 174-9 p. digitalISSN:- 0006-291X
- Amino Acid Sequence
- Amino Acid Substitution
- Antifungal Agents -- metabolism
- Candida albicans -- drug effects
- Carbon Monoxide -- metabolism
- Catalysis
- Cytochrome P-450 Enzyme Inhibitors
- Cytochrome P-450 Enzyme System -- chemistry
- Drug Resistance, Microbial
- Ergosterol -- biosynthesis
- Fluconazole -- metabolism
- Heme -- chemistry
- Inhibitory Concentration 50
- Kinetics
- Mutagenesis, Site-Directed
- Oxidation-Reduction
- Oxidoreductases -- antagonists & inhibitors
- Protein Binding
- Saccharomyces cerevisiae -- genetics
- Spectrum Analysis
- Sterol 14-Demethylase
No physical items for this record
Publication Type: Journal Article
There are no comments on this title.
Log in to your account to post a comment.