Studies with double cytokine-deficient mice reveal that highly polarized Th1- and Th2-type cytokine and antibody responses contribute equally to vaccine-induced immunity to Schistosoma mansoni. [electronic resource]
Producer: 19990729Description: 927-38 p. digitalISSN:- 0022-1767
- Animals
- Antibodies, Helminth -- biosynthesis
- Antigens, Helminth -- immunology
- Bronchi -- blood supply
- Cytokines -- biosynthesis
- Female
- Immunity, Cellular -- genetics
- Immunization, Secondary
- Interferon-gamma -- biosynthesis
- Interleukin-10 -- deficiency
- Interleukin-4 -- biosynthesis
- Larva -- immunology
- Lung -- blood supply
- Lymphocyte Subsets -- immunology
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Nitric Oxide -- biosynthesis
- Schistosoma mansoni -- growth & development
- Schistosomiasis mansoni -- genetics
- Th1 Cells -- immunology
- Th2 Cells -- immunology
- Vaccines, Attenuated -- administration & dosage
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Publication Type: Journal Article
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