Design, synthesis, and in vitro activity of catamphiphilic reverters of multidrug resistance: discovery of a selective, highly efficacious chemosensitizer with potency in the nanomolar range. [electronic resource]
Producer: 19990610Description: 1687-97 p. digitalISSN:- 0022-2623
- Animals
- Anisoles -- chemical synthesis
- Antineoplastic Agents -- chemical synthesis
- Aorta -- drug effects
- Drug Design
- Drug Resistance, Multiple
- Drug Resistance, Neoplasm
- Drug Screening Assays, Antitumor
- Heart Rate -- drug effects
- Humans
- In Vitro Techniques
- Muscle Contraction -- drug effects
- Muscle, Smooth, Vascular -- drug effects
- Nitriles -- chemical synthesis
- Rabbits
- Structure-Activity Relationship
- Tumor Cells, Cultured
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Publication Type: Journal Article
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