Design, synthesis, and in vitro activity of catamphiphilic reverters of multidrug resistance: discovery of a selective, highly efficacious chemosensitizer with potency in the nanomolar range.
Teodori, E
Design, synthesis, and in vitro activity of catamphiphilic reverters of multidrug resistance: discovery of a selective, highly efficacious chemosensitizer with potency in the nanomolar range. [electronic resource] - Journal of medicinal chemistry May 1999 - 1687-97 p. digital
Publication Type: Journal Article
0022-2623
10.1021/jm980440p doi
Animals
Anisoles--chemical synthesis
Antineoplastic Agents--chemical synthesis
Aorta--drug effects
Drug Design
Drug Resistance, Multiple
Drug Resistance, Neoplasm
Drug Screening Assays, Antitumor
Heart Rate--drug effects
Humans
In Vitro Techniques
Muscle Contraction--drug effects
Muscle, Smooth, Vascular--drug effects
Nitriles--chemical synthesis
Rabbits
Structure-Activity Relationship
Tumor Cells, Cultured
Design, synthesis, and in vitro activity of catamphiphilic reverters of multidrug resistance: discovery of a selective, highly efficacious chemosensitizer with potency in the nanomolar range. [electronic resource] - Journal of medicinal chemistry May 1999 - 1687-97 p. digital
Publication Type: Journal Article
0022-2623
10.1021/jm980440p doi
Animals
Anisoles--chemical synthesis
Antineoplastic Agents--chemical synthesis
Aorta--drug effects
Drug Design
Drug Resistance, Multiple
Drug Resistance, Neoplasm
Drug Screening Assays, Antitumor
Heart Rate--drug effects
Humans
In Vitro Techniques
Muscle Contraction--drug effects
Muscle, Smooth, Vascular--drug effects
Nitriles--chemical synthesis
Rabbits
Structure-Activity Relationship
Tumor Cells, Cultured