Expression and alteration of the S2 subsite of the Leishmania major cathepsin B-like cysteine protease. [electronic resource]
Producer: 19990630Description: 113-7 p. digitalISSN:- 0264-6021
- Amino Acid Sequence
- Animals
- Binding Sites
- Cathepsin B -- antagonists & inhibitors
- Coumarins -- metabolism
- Dipeptides -- pharmacology
- Glutamic Acid -- genetics
- Glycine -- genetics
- Humans
- Hydrogen-Ion Concentration
- Kinetics
- Leishmania major -- enzymology
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Mutation
- Pichia -- genetics
- Rats
- Recombinant Proteins -- biosynthesis
- Sequence Homology, Amino Acid
- Structure-Activity Relationship
- Substrate Specificity
- Sulfones -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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