E2F-1 has properties of a radiosensitizer and its regulation by cyclin A kinase is required for cell survival of fibrosarcoma cells lacking p53. [electronic resource]
Producer: 19990604Description: 141-6 p. digitalISSN:- 1044-9523
- Animals
- Carrier Proteins
- Cell Cycle Proteins
- Cell Line, Transformed
- Cell Survival
- DNA-Binding Proteins
- E2F Transcription Factors
- E2F1 Transcription Factor
- Fibrosarcoma -- genetics
- Gene Expression
- Genes, p53
- Mice
- Mice, Nude
- Protein Kinases -- metabolism
- Protein Synthesis Inhibitors -- metabolism
- Puromycin -- metabolism
- Radiation Tolerance -- physiology
- Retinoblastoma-Binding Protein 1
- Time Factors
- Transcription Factor DP1
- Transcription Factors -- metabolism
- Tumor Suppressor Protein p53 -- deficiency
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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