Specific inhibitors of p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways block inducible nitric oxide synthase and tumor necrosis factor accumulation in murine macrophages stimulated with lipopolysaccharide and interferon-gamma. [electronic resource]
Producer: 19990421Description: 939-44 p. digitalISSN:- 0022-1899
- Calcium-Calmodulin-Dependent Protein Kinases -- antagonists & inhibitors
- Cells, Cultured
- Dose-Response Relationship, Drug
- Flavonoids -- pharmacology
- Humans
- Imidazoles -- pharmacology
- Interferon-gamma -- pharmacology
- Lipopolysaccharides -- pharmacology
- Macrophages
- Mitogen-Activated Protein Kinases
- Nitric Oxide -- biosynthesis
- Nitric Oxide Synthase -- antagonists & inhibitors
- Nitric Oxide Synthase Type II
- Pyridines -- pharmacology
- Tumor Necrosis Factor-alpha -- antagonists & inhibitors
- p38 Mitogen-Activated Protein Kinases
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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