Identification of residues 286 and 289 as critical for conferring substrate specificity of human CYP2C9 for diclofenac and ibuprofen. (Record no. 9700248)

MARC details
000 -LEADER
fixed length control field 01804 a2200493 4500
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250513151920.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 199810s 0 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 0003-9861
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1006/abbi.1998.0826
Source of number or code doi
040 ## - CATALOGING SOURCE
Original cataloging agency NLM
Language of cataloging eng
Transcribing agency NLM
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Klose, T S
264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Date of production, publication, distribution, manufacture, or copyright notice 19981007
245 00 - TITLE STATEMENT
Title Identification of residues 286 and 289 as critical for conferring substrate specificity of human CYP2C9 for diclofenac and ibuprofen.
Medium [electronic resource]
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Name of publisher, distributor, etc. Archives of biochemistry and biophysics
Date of publication, distribution, etc. Sep 1998
300 ## - PHYSICAL DESCRIPTION
Extent 240-8 p.
Other physical details digital
500 ## - GENERAL NOTE
General note Publication Type: Journal Article
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Aryl Hydrocarbon Hydroxylases
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Cytochrome P-450 CYP2C19
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Cytochrome P-450 CYP2C9
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Cytochrome P-450 Enzyme Inhibitors
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Cytochrome P-450 Enzyme System
General subdivision genetics
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Diclofenac
General subdivision metabolism
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Enzyme Activation
General subdivision drug effects
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Escherichia coli
General subdivision genetics
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Humans
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Hydroxylation
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Ibuprofen
General subdivision metabolism
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Mixed Function Oxygenases
General subdivision genetics
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Mutagenesis, Site-Directed
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Protein Binding
General subdivision drug effects
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Recombinant Fusion Proteins
General subdivision genetics
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Steroid 16-alpha-Hydroxylase
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Steroid Hydroxylases
General subdivision antagonists & inhibitors
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Substrate Specificity
General subdivision genetics
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Tolbutamide
General subdivision metabolism
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Ibeanu, G C
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Ghanayem, B I
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Pedersen, L G
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Li, L
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Hall, S D
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Goldstein, J A
773 0# - HOST ITEM ENTRY
Title Archives of biochemistry and biophysics
Related parts vol. 357
-- no. 2
-- p. 240-8
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://doi.org/10.1006/abbi.1998.0826">https://doi.org/10.1006/abbi.1998.0826</a>
Public note Available from publisher's website

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