Design and synthesis of m1-selective muscarinic agonists: (R)-(-)-(Z)-1-Azabicyclo[2.2.1]heptan-3-one, O-(3-(3'-methoxyphenyl)-2-propynyl)oxime maleate (CI-1017), a functionally m1-selective muscarinic agonist. (Record no. 9617283)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02186 a2200685 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250513145010.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 199807s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 0022-2623 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1021/jm960683m |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Tecle, H |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 19980724 |
| 245 00 - TITLE STATEMENT | |
| Title | Design and synthesis of m1-selective muscarinic agonists: (R)-(-)-(Z)-1-Azabicyclo[2.2.1]heptan-3-one, O-(3-(3'-methoxyphenyl)-2-propynyl)oxime maleate (CI-1017), a functionally m1-selective muscarinic agonist. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Journal of medicinal chemistry |
| Date of publication, distribution, etc. | Jul 1998 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 2524-36 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | 3T3 Cells |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Adenylyl Cyclase Inhibitors |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animals |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Bridged Bicyclo Compounds, Heterocyclic |
| General subdivision | chemical synthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | CHO Cells |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cricetinae |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Drug Design |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Enzyme Inhibitors |
| General subdivision | chemical synthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Inositol Phosphates |
| General subdivision | biosynthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Male |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Memory |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Muscarinic Agonists |
| General subdivision | chemical synthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Oximes |
| General subdivision | chemical synthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Rats |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Receptor, Muscarinic M1 |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Receptors, Muscarinic |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Stereoisomerism |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Structure-Activity Relationship |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Transfection |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Barrett, S D |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lauffer, D J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Augelli-Szafran, C |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Brann, M R |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Callahan, M J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Caprathe, B W |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Davis, R E |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Doyle, P D |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Eubanks, D |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lipiniski, W |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mirzadegan, T |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Moos, W H |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Moreland, D W |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Nelson, C B |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Pavia, M R |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Raby, C |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Schwarz, R D |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Spencer, C J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Thomas, A J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Jaen, J C |
| 773 0# - HOST ITEM ENTRY | |
| Title | Journal of medicinal chemistry |
| Related parts | vol. 41 |
| -- | no. 14 |
| -- | p. 2524-36 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1021/jm960683m">https://doi.org/10.1021/jm960683m</a> |
| Public note | Available from publisher's website |
No items available.