Class III antiarrhythmic activity in vivo by selective blockade of the slowly activating cardiac delayed rectifier potassium current IKs by (R)-2-(2,4-trifluoromethyl)-N-[2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)- 2, 3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]acetamide. (Record no. 9366851)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02046 a2200613 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250513132243.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 199801s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 0022-2623 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1021/jm970517u |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Selnick, H G |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 19980112 |
| 245 00 - TITLE STATEMENT | |
| Title | Class III antiarrhythmic activity in vivo by selective blockade of the slowly activating cardiac delayed rectifier potassium current IKs by (R)-2-(2,4-trifluoromethyl)-N-[2-oxo-5-phenyl-1-(2,2,2-trifluoroethyl)- 2, 3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]acetamide. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Journal of medicinal chemistry |
| Date of publication, distribution, etc. | Nov 1997 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 3865-8 p. |
| Other physical details | digital |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Acetamides |
| General subdivision | chemical synthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Administration, Oral |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animals |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Anti-Arrhythmia Agents |
| General subdivision | chemical synthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Benzodiazepinones |
| General subdivision | chemical synthesis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cells, Cultured |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Dogs |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Electrocardiography, Ambulatory |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Guinea Pigs |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Heart |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Myocardium |
| General subdivision | cytology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Potassium Channel Blockers |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Potassium Channels |
| General subdivision | physiology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Xenopus |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Liverton, N J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Baldwin, J J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Butcher, J W |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Claremon, D A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Elliott, J M |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Freidinger, R M |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | King, S A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Libby, B E |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | McIntyre, C J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Pribush, D A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Remy, D C |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Smith, G R |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Tebben, A J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Jurkiewicz, N K |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lynch, J J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Salata, J J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sanguinetti, M C |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Siegl, P K |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Slaughter, D E |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Vyas, K |
| 773 0# - HOST ITEM ENTRY | |
| Title | Journal of medicinal chemistry |
| Related parts | vol. 40 |
| -- | no. 24 |
| -- | p. 3865-8 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1021/jm970517u">https://doi.org/10.1021/jm970517u</a> |
| Public note | Available from publisher's website |
No items available.