Structure-based design of substituted diphenyl sulfones and sulfoxides as lipophilic inhibitors of thymidylate synthase. (Record no. 9045898)

MARC details
000 -LEADER
fixed length control field 02218 a2200697 4500
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20250513112955.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 199704s 0 0 eng d
022 ## - INTERNATIONAL STANDARD SERIAL NUMBER
International Standard Serial Number 0022-2623
024 7# - OTHER STANDARD IDENTIFIER
Standard number or code 10.1021/jm960613f
Source of number or code doi
040 ## - CATALOGING SOURCE
Original cataloging agency NLM
Language of cataloging eng
Transcribing agency NLM
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Jones, T R
264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Date of production, publication, distribution, manufacture, or copyright notice 19970417
245 00 - TITLE STATEMENT
Title Structure-based design of substituted diphenyl sulfones and sulfoxides as lipophilic inhibitors of thymidylate synthase.
Medium [electronic resource]
260 ## - PUBLICATION, DISTRIBUTION, ETC.
Name of publisher, distributor, etc. Journal of medicinal chemistry
Date of publication, distribution, etc. Feb 1997
300 ## - PHYSICAL DESCRIPTION
Extent 677-83 p.
Other physical details digital
500 ## - GENERAL NOTE
General note Publication Type: Journal Article
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Animals
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Antineoplastic Agents
General subdivision chemical synthesis
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Cell Division
General subdivision drug effects
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Crystallography, X-Ray
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Drug Screening Assays, Antitumor
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Enzyme Inhibitors
General subdivision chemical synthesis
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Escherichia coli
General subdivision enzymology
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Humans
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Magnetic Resonance Spectroscopy
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Mice
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Models, Molecular
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Molecular Conformation
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Molecular Structure
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Neoplasms, Experimental
General subdivision drug therapy
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Quinazolines
General subdivision chemical synthesis
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Structure-Activity Relationship
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Sulfones
General subdivision chemical synthesis
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Sulfoxides
General subdivision chemical synthesis
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Thymidylate Synthase
General subdivision antagonists & inhibitors
650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element Tumor Cells, Cultured
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Webber, S E
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Varney, M D
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Reddy, M R
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Lewis, K K
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Kathardekar, V
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Mazdiyasni, H
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Deal, J
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Nguyen, D
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Welsh, K M
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Webber, S
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Johnston, A
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Matthews, D A
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Smith, W W
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Janson, C A
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Bacquet, R J
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Howland, E F
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Booth, C L
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Herrmann, S M
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Ward, R W
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name White, J
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Bartlett, C A
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Morse, C A
773 0# - HOST ITEM ENTRY
Title Journal of medicinal chemistry
Related parts vol. 40
-- no. 5
-- p. 677-83
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="https://doi.org/10.1021/jm960613f">https://doi.org/10.1021/jm960613f</a>
Public note Available from publisher's website

No items available.