An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice. (Record no. 30820717)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02937 a2200865 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20250518094218.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 202005s 0 0 eng d |
| 022 ## - INTERNATIONAL STANDARD SERIAL NUMBER | |
| International Standard Serial Number | 1946-6242 |
| 024 7# - OTHER STANDARD IDENTIFIER | |
| Standard number or code | 10.1126/scitranslmed.abb5883 |
| Source of number or code | doi |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | NLM |
| Language of cataloging | eng |
| Transcribing agency | NLM |
| 100 1# - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Sheahan, Timothy P |
| 264 #0 - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE | |
| Date of production, publication, distribution, manufacture, or copyright notice | 20200504 |
| 245 00 - TITLE STATEMENT | |
| Title | An orally bioavailable broad-spectrum antiviral inhibits SARS-CoV-2 in human airway epithelial cell cultures and multiple coronaviruses in mice. |
| Medium | [electronic resource] |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Name of publisher, distributor, etc. | Science translational medicine |
| Date of publication, distribution, etc. | 04 2020 |
| 500 ## - GENERAL NOTE | |
| General note | Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Adenosine Monophosphate |
| General subdivision | administration & dosage |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Alanine |
| General subdivision | administration & dosage |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Animals |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Antibiotic Prophylaxis |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Antiviral Agents |
| General subdivision | administration & dosage |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Betacoronavirus |
| General subdivision | physiology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | COVID-19 |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cell Line |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Coronavirus Infections |
| General subdivision | drug therapy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Cytidine |
| General subdivision | administration & dosage |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Disease Models, Animal |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Drug Resistance, Viral |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Humans |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Hydroxylamines |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Lung |
| General subdivision | pathology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mice, Inbred C57BL |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Middle East Respiratory Syndrome Coronavirus |
| General subdivision | physiology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Models, Molecular |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Mutation |
| General subdivision | drug effects |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pandemics |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Pneumonia, Viral |
| General subdivision | drug therapy |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Primary Cell Culture |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | RNA, Viral |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | RNA-Dependent RNA Polymerase |
| General subdivision | chemistry |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Random Allocation |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Respiratory System |
| General subdivision | cytology |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Ribonucleosides |
| General subdivision | administration & dosage |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | SARS-CoV-2 |
| 650 04 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name entry element | Virus Replication |
| General subdivision | drug effects |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Sims, Amy C |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Zhou, Shuntai |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Graham, Rachel L |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Pruijssers, Andrea J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Agostini, Maria L |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Leist, Sarah R |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Schäfer, Alexandra |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Dinnon, Kenneth H |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Stevens, Laura J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Chappell, James D |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Lu, Xiaotao |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hughes, Tia M |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | George, Amelia S |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Hill, Collin S |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Montgomery, Stephanie A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Brown, Ariane J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Bluemling, Gregory R |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Natchus, Michael G |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Saindane, Manohar |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Kolykhalov, Alexander A |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Painter, George |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Harcourt, Jennifer |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Tamin, Azaibi |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Thornburg, Natalie J |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Swanstrom, Ronald |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Denison, Mark R |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Baric, Ralph S |
| 773 0# - HOST ITEM ENTRY | |
| Title | Science translational medicine |
| Related parts | vol. 12 |
| -- | no. 541 |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | <a href="https://doi.org/10.1126/scitranslmed.abb5883">https://doi.org/10.1126/scitranslmed.abb5883</a> |
| Public note | Available from publisher's website |
No items available.